Nigel Pearson's men missed out on the play-offs by 10 points last term and will be hoping to pour further misery on the Seasiders, who suffered final-day relegation heartbreak in May.
Hull travel to face Middlesbrough at The Riverside on Boxing Day before hosting the Teessiders on 9 April.
The Tigers visit Upton Park to take on divisional giants West Ham on the final day of the campaign on 28 April.
Source: Team Talk
Source: Team Talk