Justin Whittle will return to the Tigers' rearguard. He will partner either Mark Greaves or Nicky Mohan in central defence.
Defenders Ian Goodison and Matt Wicks will still be absent from the squad because of injury. Mike Edwards should be fit after shaking off a slight knock.
Forwards Lawrie Dudfield and Rodney Rowe could make their long-awaited returns to the squad.
Expected line-up (4-4-2): Musselwhite; Edwards, Whittle, Greaves, Van Blerk; Williams, Petty, Sneekes, Holt; Alexander, Bradshaw.
Subs from: Glennon, Mohan, Burton, Peat, Morley, Matthews, Johnsson, Philpott, Beresford, Norris, Whitmore, Caceres, Dudfield, Rowe.
Promotion: Get Hull City shirts from the 40s, 50s and 60s at RetroFC.