The Shrimpers made it 4 wins from their last 6 league games with a 5-0 thrashing of QPR at Roots Hall.
Southend remain 2nd from bottom and equal City's 31 points thus far, though have played an extra game than the Tigers and have an inferior goal difference.
Leeds are now 4 points adrift at the bottom of the table, but have 2 games in hand of Southend.
QPR remain in 19th place on 33 points. 20th placed Luton's game against Norwich tomorrow has been postponed, while 21st placed Barnsley face Colchester.